- Although working under the general guidance of an academic or Principal Investigator, they should contribute with new ideas, including enhancements to the technical or methodological aspects of their studies, thus providing substantial ‘added value’
- Determine appropriate methodologies for research, with advice and support where required
- Develop and carry out the specified project (analysis of transcriptomic, proteomic and genomic datasets) using appropriate bioinformatic techniques and equipment as outlined in the personal requirements
- Assess research findings for the need/scope for further investigations
- Contribute to the writing up of their research and its dissemination, either through seminar and conference presentations or through publications
- Present research findings, either at conferences or through publications in reputable outlets appropriate to the discipline
- Contribute to grant applications submitted by others and develop their own research objectives and proposals for funding
- Involvement in the supervision, with guidance, of final year undergraduate research projects and in providing support to postgraduate research students or Research Assistants
- Start to develop an awareness of University structures, policies and procedures and relevant issues in the higher education, research, social and political environment
- Write, with appropriate support, proposals for individual research funding or, where funders do not permit this, contribute to the writing of collective bids
- May contribute to events celebrating the public engagement of science/social sciences/humanities
- Will need to work with the support staff and, on occasions, with undergraduate and postgraduate students, and interact intellectually with other academic members of the Institute
- Support a range of research activities across the JWMDRC, besides the specified project
- Provide guidance on ongoing and future research, particularly experimental design, omics data analysis and interpretation
- Keep up to date with new developments in the bioinformatics field and apply them to the diverse range of data generated within the JWMDRC lab
- Communicate methodologies and analyses to a wide audience, including clinical, laboratory and informatics researchers, as well as non-experts
Hands-on experience in the analysis of large-scale omics data, including complex multistage pipeline development, reporting, and troubleshooting
- Experience with single cell/single nuclei RNA sequencing and spatial transcriptomics datasets
- Proficiency in programming (e.g., using Linux/Python and R), command-line applications, and programming standards such as version control
- Excellent written and oral communication skills in English, with the ability to present to technical and non-technical audiences
- Detailed subject knowledge in bioinformatics
- Detailed subject knowledge in biology
- Understanding of the application of statistical methods to omics studies
- Experience with the research environment (design and delivery of research projects)
- Presentations at conferences and/or high-quality publications
- Ability to prepare and maintain detailed documentation of their work
- Experience with epigenetic, proteomic and genomic datasets
- Experience in integrative omics methodologies
- Experience accessing and utilising external, publicly available datasets (e.g., Genomics England, UKBioBank, EBI)
- Familiarity with containerisation (e.g., Docker) of informatic pipelines/workflows
- Understanding and/or experience with other complex datasets, including integration of health records or phenotypic data
- Experience in working in a multidisciplinary team (e.g., a team involving clinicians, scientists, etc.) and/or in wider collaborative groups
- Subject knowledge in muscle biology and pathophysiology of muscle diseases
- Experience in working with human tissue samples
- Enthusiastic, hardworking and able to take initiative
- Ability to work independently and as part of a team
- Excellent problem solving and analytical skills
- Capability to develop new skills
- Ability to communicate complex information with clarity and to encourage the commitment of others
- Good time management and ability to prioritise to meet deadlines
- A PhD in bioinformatics, biology or related field, and experience in the research area required (Research Associate Level)
- Good honours degree (or equivalent) (or equivalent) or close to submission of PhD (Research Assistant Level)