Medical Director

• Great opportunity to join a leading Australian biotech company. 
• Lead asset advancing through phase 1 clinical development.
• Join a world class team to make a difference in treatment of cancers with high unmet need.

ImmVirX is developing novel oncolytic viruses to create powerful new cancer immunotherapy combinations. Its novel oncolytic immunotherapy harnesses the power of viruses to preferentially infect and kill cancer cells and induce systemic anti-tumour immune responses.

The proprietary bio-selected RNA viruses target specific receptor proteins highly expressed on a range of cancer cell types, allowing them to selectively enter, replicate in, and destroy tumour cells while creating beneficial changes in the tumour micro-environment, potentially leading to the generation of specific innate and adaptive immune responses against cancer cells.  

In this way, the viral candidates are intended to increase the effectiveness of current immunotherapies, primarily immune checkpoint inhibitors and CAR-T cell therapies, in fighting cancers of high unmet need including colorectal, gastric, ovarian and liver cancer.

This is a high growth, fast paced small organization. The ability to be productive and successful in a dynamic work environment is critical. Willingness and ability to travel domestically and internationally is required. The role will be based in Australia. The company is willing to be flexible about location, provided the candidate is able to readily meet the travel requirements of the role. 

www.immvirx.com

The Medical Director reports directly to the Chief Executive Officer. The primary role of the Medical Director will be to provide leadership and direction for ImmVirX’s clinical development programs and medical activities and represent the Company to the medical community, health authorities and investors. The Medical Director is a key member of the company’s executive team which determines and oversees research and development at ImmVirX and helps set the overall strategic direction of the company.

Key Responsibilities: 
Promoting the company’s clinical programme within the oncology community in order to drive clinician interest and patient recruitment.

• Responsibility across Clinical Development, Clinical Operations, Biometrics, Safety and Medical Affairs (some of these activities are managed through consultants and contractors supplementing in-house resources).
• Close collaboration with CSO (inventor of the technology)
• Leadership in setting clinical strategy.
• Cross-functional engagement with R&D, Regulatory and Corporate departments.
• Providing strategic medical input into development of the company's key assets. 
• Developing and maintaining strong, collaborative relationships with key internal and external stakeholders and industry thought leaders.
• Collaborating with CSO and Principal Investigators on all facets of the program, including evaluation and assessment of:
  
  • emerging clinical experiences and trends 
  • relevant scientific and clinical publications 
  • potential synergistic opportunities for the company’s assets
  • communication of emerging clinical data
• Participating in presenting company data to investors and generally representing the Company and its programs to external audiences, including the investment, medical and regulatory communities.
• Directing the development of clinical strategies and plans to integrate the ImmVirX product portfolio into the standard practice of treatment for several oncology indications as appropriate.
• Managing clinical aspects of regulatory strategies and interactions with relevant health authorities to successfully deliver studies on budget and on time. 
• Overseeing the analysis and interpretation of clinical trial data and the reporting of clinical trial results. Lead interactions with academic thought leaders, investigators, cooperative groups, and other clinical stakeholders.

• Well-rounded, driven physician with deep experience in oncology in particular cancer immunotherapy 
• Australia-based with ability to travel frequently. We are flexible about workplace location.
• Ability to work in a collegial and collaborative company which develops its technology in-house. Proven skills as an effective team player who is prepared to be ‘hands on’ and can engender credibility and confidence within and outside the company. 
• Working knowledge of the clinical drug development process, ideally through participation in clinical trials. Thorough knowledge of clinical research concepts, practices, and guidelines. 
• Solid relationships with key opinion leaders (KOLs) in the oncology therapeutic community. 
• Knowledge of relevant TGA, FDA regulations and guidelines and ideally those of the EU and other health authorities. 
• Excellent knowledge of therapies in the oncology marketplace and R&D pipelines. 
• Read, write and speak fluent English and possess excellent communication skills. 
• Excellent leadership, people management and interpersonal skills. 
• Science and data driven. Able to develop and implement a program for scientific publications and conference presentations. 
• Strong focus on quality. 
• High personal values and ethical standards in line with ImmVirX’s Code of Conduct.

• MBBS (FRACP) qualifications in oncology and 5+ years’ experience in clinical practice treating patients including working on investigational new drugs.
• Management experience within a clinical group including responsibilities in medical affairs and clinical operations.
• Proven record in clinical research studies and trial design including experience in submission of regulatory filings relevant to trial initiation and management. 
   

For enquiries please contact Dr Malcolm McColl at **************@immvirx.com or on 0478 202 ***.